Most people who have asthma know that smoke, mold, and chemicals in the air can make it difficult to
 breathe. But what about thunderstorms? It's a bit of a mystery, but over the years studies by climatologists
 and epidemiologists have shown a spike in asthma attacks after stormy weather
 Question
 In the third sentence, "spike" most nearly means
 disappearance
 O brief increase
 O negation
 O sudden interruption