You want to divide by avagadros number (6.22 x 10^23). This will cancel the atoms unit and give moles, moles of Iridium. Now you want to calculate the atomic mass of Iridium which is in units of grams per mole. Multiply these two numbers and the moles will cancel giving you grams.
Setting up a dimension analysis type of thing helps tremendously. See what you have to cancel in order to get what you want. We canceled the atoms, then we canceled the moles, and then we got grams.