Question

A mutation of the proteolytic enzyme Trypsin results in a stable covalent bond between one of the catalytic amino acids of the protease and its protein substrate. Which of the following are probably true?

a. The enzyme would become inactive.
b. The enzyme and substrate would be stuck together.
c. The delta-G of the proteolysis reaction would change.
d. The rate of the catalyzed reaction would increase.

Answer 1

b. The enzyme and substrate would be stuck together.