Question

Based on the pedigree that is shown above, how to describe Fred?

Answer 1

The given pedigree analysis shows sex-linked trait where the female work as a carrier and have X linked recessive gene that is
`X^(h)` and the male is normal.

So, Fred will be a male with
`X^(h)`
`Y` gene and Fred will be affected with X linked disease which is carried by female.

If,
`X^(h)` gene in the female (Ann) act as a carrier of hemophilia and the male (John) is normal, then Fred will be a male affected with hemophilia (sex linked disease).

Hence, Fred will be affected male with
`X^(h)`
`Y` genotype.