Question

Which of the following statements is FALSE?

a.Cdk7 of the CAK (TFIIH component) phosphorylates Cyclin 8 of the Mediator to down regulate promoter activity.
b.TFIIF (RAP74 RAP30) show similarity to sigma 70 domains 2 and 3.
c.TFIIF has affinity for the zinc-ribbon at the N-terminus of TFIIB.
d.Archaea have a factor nearly identical to TFIIB called TFB.
e.Mediator binds the CTD of RNA pol II when the CTD is hypophosphorylated and leaves when the CTD becomes hyperphosphorylated.

Answer 1

Answer is A. Cdk7 of the CAK (TFIIH component) phosphorylates Cyclin 8 of the Mediator to down regulate promoter activity.

Refer below.

Step-by-step explanation:

Cdk7 of the CAK (TFIIH component) phosphorylates Cyclin 8 of the Mediator to down regulate promoter activity is a FALSE STATEMENT.