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5 votes
Why does the tlc chamber need to be capped while the tlc plate is developing?

1 Answer

0 votes
This has to do with the vapor pressure of the solvent. If there's no cap, the pressure of the TLC chamber is too low and it won't travel up the TLC plate. So always use a lid. It doesn't have to be air-tight; simply putting a watch glass over a 50 or 100 mL beaker will do just fine.
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