The correct answer is: c. A decreasing PSA.
PSA (Prostate-Specific Antigen) is a protein made by the prostate. An increase in PSA can indicate the presence of prostate cancer. A declining PSA, however, indicates an improvement in the condition, possibly indicating a slowing or regression of the cancer. A high level of PSA that remains the same is considered a negative sign, indicating that the cancer may be stable or even growing.