Question

Which mutation would likely have the smallest effect on an individual's phenotype? A. A substitution near the end of a gene B. A frameshift mutation that produces an early stop codon C. An insertion near the beginning of a gene D. A deletion that leads to misfolding of a protein​

Answer 1

B is the mutation that is more likely to have a greater impact on a phenotype. a frameshift mutation that resulted in protein misfolding.