Question

Signal transducers and activators of transcription (STATS) are

latent transcription regulators, meaning they require
activation in order to function. What is the name of the domain
that is responsible

Answer 1

Step-by-step explanation:

The transcription factor Stp1 is endoproteolytically processed in response to extracellular amino acids by the plasma membrane SPS (Ssy1–Ptr3–Ssy5)-sensor. Processed Stp1, lacking a cytoplasmic retention motif, enters the nucleus and induces amino acid transporter gene expression. The SPS-sensor component Ssy5 is a chymotrypsin-like protease with a Pro-domain and a catalytic domain. The Pro-domain, required for protease maturation, is autolytically cleaved from the catalytic domain but remains associated, forming an inactive protease complex that binds Stp1. Stp1 is processed only after amino acid-induced signals cause the dissociation of the inhibitory Pro-domain. Our findings demonstrate that gene expression can be controlled by regulating the enzymatic activity of an intracellular endoprotease.

Keywords: Saccharomyces cerevisiae, environmental sensing, signal transduction, regulated proteolysis