Answer:
For the coefficients, the prime factorization of 50 is 2 x 5 x 5, and the prime factorization of 125 is 5 x 5 x 5. The common factors are 5 x 5 = 25.
For the variables, we can find the lowest exponent of each variable that appears in both terms.
The variable x appears in both terms, with exponents of 5 and 3. The lowest exponent is 3.
The variable y appears in both terms, with exponents of 2 and 3. The lowest exponent is 2.
The variable z appears in both terms, with exponents of 2 and 1. The lowest exponent is 1.
Therefore, the GCF of 50x^5y^2z^2 and 125x^3y^3z is 25x^3y^2z.