Question

Which of the following opioids is semisynthetic, created by adding two acetyl groups to the morphine molecule?

A) heroin
B) codeine
C) oxycodone
D) fentanyl
E) methadone

Answer 1

A) heroin

Heroin is a semisynthetic opioid created by adding two acetyl groups to the morphine molecule. This modification increases its potency and ability to cross the blood-brain barrier, leading to a faster onset and more intense effects compared to morphine.