Final answer:
The main difference between modern and classical biotechnology is that modern biotechnology involves recombinant DNA technology, genetic manipulation, and living organisms, while classical biotechnology does not.
Step-by-step explanation:
The main difference between modern and classical biotechnology is that modern biotechnology involves recombinant DNA technology, genetic manipulation, and living organisms, while classical biotechnology does not.
Modern biotechnology allows scientists to directly alter an organism's genome through genetic engineering, creating new combinations of genetic material.
It also involves the use of living organisms in processes such as fermentation. On the other hand, classical biotechnology focuses on traditional breeding methods without genetic manipulation.