Final answer:
CD4+ T cells recognize antigenic peptides presented by Major Histocompatibility Complex (MHC) II molecules on antigen-presenting cells (APCs).
Step-by-step explanation:
Antigens are processed and fragmented inside these APCs, and the antigen fragments are then presented on the surface of the APCs along with MHC II molecules. CD4+ T cells recognize antigenic peptides presented by Major Histocompatibility Complex (MHC) II molecules on antigen-presenting cells (APCs).
When a CD4+ T cell encounters an antigen-presenting cell with the appropriate antigen-MHC II complex, the T cell receptor on the CD4+ T cell recognizes and binds to the complex, initiating an immune response.