Question

Autoimmune diseases such as Type 1 diabetes, RA, and MS are common, often devastating diseases. The key feature of these diseases is the development and persistence of inflammatory processes in the apparent absence of pathogens, leading to destruction of the target tissue. Presently no comprehensive explanation can be given for the onset of autoimmune disease. As a rule, the chronic activation of a particular type of cell appears to be crucial for fueling the destructive autoimmune processes. What is this cell type?

T helper cells
T suppressor cells
Macrophages
Dendritic cells
Basophils

Answer 1

The key cell type involved in autoimmune diseases is T helper cells.

Step-by-step explanation:

The key feature of autoimmune diseases is the development and persistence of inflammatory processes in the apparent absence of pathogens, leading to destruction of the target tissue. The chronic activation of a particular type of cell appears to be crucial for fueling the destructive autoimmune processes, and this cell type is T helper cells. T helper cells play a key role in the immune response by coordinating and regulating the actions of other cells of the immune system.

Answer 2

In autoimmune diseases, the chronic activation of T Helper cells is critical to the inflammatory processes that cause tissue destruction. Autoimmune conditions like Type 1 diabetes, RA, and MS involve these cells attacking the body's own tissues, and treatments usually involve managing symptoms with anti-inflammatory medications.

So, the correct answer is 1) T helper cells.

Step-by-step explanation:

The chronic activation of a particular type of cell is crucial in fueling destructive autoimmune processes. This cell type is the T Helper cell, often specifically the Th1 subset. In autoimmune diseases such as Type 1 diabetes, Rheumatoid Arthritis (RA), and Multiple Sclerosis (MS), these T Helper cells play a fundamental role in perpetuating the inflammation and damage to the body's tissues.

Autoimmune diseases manifest when the immune system mistakenly attacks the body's own tissues, mistaking them for harmful pathogens. This breakdown in the immune system's tolerance leads to conditions where T Helper cells are mistakenly activated against self-antigens, resulting in chronic inflammation and tissue destruction.

Treatments for autoimmune diseases often involve anti-inflammatory drugs and immunosuppressive medications to manage symptoms, as they cannot typically be cured. The specific autoimmune disorder depends on which body tissues are affected, and the symptoms can vary widely among patients.

So, the correct answer is 1) T helper cells.