Question

Cytokines are similar to polypeptide hormones, since they facilitate communication between cells and do so at very low concentrations. Cytokines are short-lived and may act locally either on the same cell that secreted them or other cells, or, like hormones, they may act systemically. More than 25 cytokines have now been identified that exhibit some sort of hematopoietic activity. Several have been identified with stimulatory activity on platelet production. What is one of these?

EPO
G-CSF
M-CSF
TPO
RANTES

Answer 1

Thrombopoietin (TPO) is a cytokine with stimulatory activity on platelet production. It is crucial for the development of megakaryocytes into platelets and is produced by the liver and kidneys.The correct option is D .

Step-by-step explanation:

Cytokines are glycoproteins that play an essential role in cell communication and the regulation of cell growth, especially concerning the body's immune responses and blood cell formation, known as hemopoiesis.

One cytokine identified with stimulatory activity on platelet production is Thrombopoietin (TPO). TPO is produced by the liver and kidneys and is responsible for the development of megakaryocytes into platelets.

Colony-stimulating factors (CSFs), another subtype of cytokines, include several forms like granulocyte CSF, monocyte CSF, and granulocyte-macrophage CSF (GM-CSF); Multi-CSF stimulates the production of various blood cells, including platelets.

These CSFs can be used in medical treatments to help increase white blood cell counts in cancer patients undergoing chemotherapy.The correct option is D.