Final answer:
Stereoisomers with two asymmetric centers and one shared configuration while the other center's configuration is opposite are called diastereomers.
Step-by-step explanation:
Stereoisomers with two asymmetric centers are called diastereomers if one of the asymmetric centers has the same configuration in both stereoisomers and the other asymmetric center has the opposite configuration in the two stereoisomers. Stereoisomers that are related as non-superimposable mirror images are known as enantiomers. Molecules with two asymmetric centers can exist as multiple stereoisomers; for example, but-2-ene can be present in both cis and trans configurations, which are diastereomers of each other because they do not mirror each other. Configurational isomers, such as diastereomers, can only be converted into each other by breaking and making bonds, indicating a chemical change. Chiral molecules with asymmetric centers are non-superimposable mirror images known as enantiomers, with the example showing how glucose, with four asymmetric centers, can have multiple isomers.