Final answer:
The disorder with the greatest comorbidity with pathological gambling is major depressive disorder. Imbalances of neurotransmitters like serotonin and norepinephrine contribute to both conditions, and abundant research supports this association.
Step-by-step explanation:
The question asks which disorder has the greatest comorbidity with pathological gambling. Based on the available research, the correct answer is D. Major depressive disorder. Pathological gambling often co-occurs with various psychiatric conditions; however, major depressive disorder has been found to have a particularly high comorbidity rate with pathological gambling.
Pathological gambling involves an inability to resist impulses to gamble, which can lead to severe personal and social consequences. Neurotransmitter imbalances, such as those involving serotonin and norepinephrine, may contribute to the compulsive behavior associated with gambling addiction. These neurotransmitters are involved in regulating mood and decision-making processes, and their dysregulation could play a role in the development or exacerbation of both major depressive disorder and pathological gambling.
The evidence points toward major depressive disorder as the mental health condition most commonly found in individuals with pathological gambling issues. For instance, Al-Asadi, Klein, and Meyer (2015) found multiple comorbidities among different psychological disorders, and research often indicates an association between depressive disorders and pathological gambling.