Question

Write the sequence for the coding and template DNA strands of this RNA molecule including orientation 5'-CCUGAUAAUCGGCUCC-3'

A) Coding: 5'-CCUGAUAAUCGGCUCC-3'; Template: 5'-CCUGAUAAUCGGCUCC-3'
B) Coding: 5'-CCUGAUAAUCGGCUCC-3'; Template: 3'-GGACUAUUAGCCGAGG-5'
C) Coding: 3'-GGACUAUUAGCCGAGG-5'; Template: 5'-CCUGAUAAUCGGCUCC-3'
D) Coding: 3'-GGACUAUUAGCCGAGG-5'; Template: 3'-GGACUAUUAGCCGAGG-5'

Answer 1

The template DNA strand that matches the given RNA sequence 5'-CCUGAUAAUCGGCUCC-3' is 3'-GGACTATTAAGCCAGG-5'. The coding DNA strand is 5'-CCATATTAGGCTCC-3', sharing the same sequence as the RNA but with thymine (T) replacing uracil (U).

Step-by-step explanation:

The given RNA molecule is 5'-CCUGAUAAUCGGCUCC-3'. To find the template DNA strand, we must remember that RNA is transcribed from a DNA template strand in a complementary and antiparallel manner. Thus, we must find the DNA sequence that is complementary to the RNA molecule but oriented in the reverse direction since DNA and RNA are antiparallel.

We replace RNA uracil (U) with DNA thymine (T) and use the complementary base-pair rules where adenine (A) pairs with thymine (T) and cytosine (C) pairs with guanine (G). So the template DNA strand for the RNA sequence is 3'-GGACTATTAAGCCAGG-5' (complementary and antiparallel).

The coding DNA strand is the non-template strand, which actually has the same sequence as the RNA but with uracil (U) replaced by thymine (T). Therefore, the coding DNA strand that would match the RNA sequence is 5'-CCATATTAGGCTCC-3' (again, complementary and oriented in the same direction as the RNA).

The correct answer is not directly listed in the options provided, but the process for determining those sequences is outlined here.