asked 194k views
5 votes
A physician that you work with tells you about a patient with PD who is new to her. The patient is exhibiting symptoms of mild cognitive impairment and depression. What antidepressant would you suggest avoiding so as to not increase the risk of cognitive impairment in this patient?

A) Bupropion
B) Mirtazapine
C) Paroxetine
D) Venlafaxine

1 Answer

5 votes

Final answer:

When prescribing antidepressants for a patient with Parkinson's Disease and mild cognitive impairment, tricyclic antidepressants should be avoided due to their anticholinergic side effects that can worsen cognitive symptoms. SSRIs are generally a safer choice for such patients. Treatment should be individualized, integrating psychotherapy and other non-pharmacological strategies.

Step-by-step explanation:

When working with a patient with Parkinson's Disease (PD) who is exhibiting symptoms of mild cognitive impairment and depression, certain antidepressants should be avoided to not increase the risk of cognitive impairment. Tricyclic antidepressants (TCAs) are known for their potential anticholinergic side effects, which can exacerbate cognitive issues. These medications may cause sedation, confusion, and difficulty in concentrating, which would not be conducive to the condition of a patient already suffering from mild cognitive impairment.

Therefore, while selecting an antidepressant for a PD patient with these symptoms, it's better to consider other classes of medications, such as selective serotonin reuptake inhibitors (SSRIs), which generally have fewer cognitive side effects. Strategies to treat depression include not only medications but also psychotherapy, exercise, and other forms of brain stimulation therapy, avoiding the one-size-fits-all approach and tailoring the treatment to the patient's specific needs and medical profile.

answered
User Doynax
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