Question

How do beta-lactam antibiotics interfere with the active sites in bacteria?

A) By binding to and inhibiting the DNA replication machinery
B) By disrupting the cell membrane structure
C) By competitively binding to and inhibiting penicillin-binding proteins (PBPs)
D) By inhibiting bacterial RNA synthesis

Answer 1

Beta-lactam antibiotics interfere with the active sites in bacteria by competitively binding to and inhibiting penicillin-binding proteins (PBPs).

Step-by-step explanation:

Beta-lactam antibiotics interfere with the active sites in bacteria by competitively binding to and inhibiting penicillin-binding proteins (PBPs). Penicillin-binding proteins are enzymes involved in the cell wall synthesis of bacteria. By inhibiting these proteins, beta-lactam antibiotics prevent the formation of a functional cell wall, leading to the death of the bacteria.