Final answer:
Osteoclasts, which are multinucleated cells involved in bone resorption, are predominantly located on the surfaces of bones.
Step-by-step explanation:
Osteoclasts are multinucleated cells that play a crucial role in the resorption of bone tissue. They are primarily found on the surfaces of bones, where they break down bone by dissolving its minerals and releasing them into the bloodstream. This process of bone resorption by osteoclasts is essential for bone remodeling, repair, and calcium homeostasis. Osteoclasts are formed from monocytes and macrophages, which are types of white blood cells, and not from osteogenic cells. Additionally, osteoclast activity is regulated by various hormones, such as parathyroid hormone and thyroid hormones, which stimulate resorption, and by calcitonin and estrogens, which inhibit it.