Final answer:
In the medication Advair, corticosteroids bind to glucocorticoid receptors to form complexes that alter gene expression to reduce inflammation.
Step-by-step explanation:
In the context of the medication Advair, corticosteroids bind to glucocorticoid receptors within the body to form complexes that lead to the modulation of gene expression. Advair contains the corticosteroid fluticasone propionate, which, once bound to its receptor, can enter the cell nucleus and bind to DNA, influencing the transcription of various genes involved in the inflammatory response. This process results in a reduction of inflammation and is part of the mechanism through which Advair helps in the management of asthma and chronic obstructive pulmonary disease (COPD).