Final answer:
Opioid withdrawal symptoms typically start within 8-12 hours after the last oxycodone dose, with the peak of symptoms around 72 hours.
Step-by-step explanation:
The withdrawal symptoms from opioids like oxycodone (OxyContin) typically begin within 8-12 hours after the last dose and peak around 72 hours. For a patient who has been taking oxycodone regularly for a sustained period such as 8 weeks, one can generally anticipate that withdrawal symptoms will likely begin within the 8-12 hour window. These symptoms can include cravings, anxiety, nausea, muscle aching, and an increased heart rate.