Question

Inheritance of Ornithine Transcarbamylase Deficiency?

A) Autosomal Recessive
B) X-Linked Recessive
C) Autosomal Dominant
D) X-Linked Dominant

Answer 1

Ornithine Transcarbamylase Deficiency is an X-linked recessive disorder caused by a deficiency of the enzyme ornithine transcarbamylase. Males are more severely affected, while females can be carriers without symptoms.

Step-by-step explanation:

Ornithine Transcarbamylase Deficiency is an inherited disorder caused by a deficiency of the enzyme ornithine transcarbamylase. This enzyme is involved in the breakdown and removal of ammonia from the body. The inheritance pattern of this disorder is X-linked recessive. It means that the gene that is responsible for ornithine transcarbamylase deficiency is located on the X chromosome, and individuals with one copy of the abnormal gene (males) or two copies of the abnormal gene (females) will have the disorder. Males are more severely affected due to the presence of a single X chromosome, whereas females may be carriers without showing symptoms.