Final answer:
The estimated daily intake of statins from drinking water is 2.54 μg/day, which is significantly lower than the minimum therapeutic dose of 5 mg/day. This means that the concentration of statins in drinking water is too low to have a therapeutic effect.
Step-by-step explanation:
To calculate the estimated daily intake of statins from drinking water, we need to multiply the concentration of statins in drinking water by the volume of water consumed. The concentration of statins in drinking water is 1.27 μg/L, and the average person drinks 2 L of water per day. Therefore, the estimated daily intake of statins from drinking water is 1.27 μg/L x 2 L/day = 2.54 μg/day.
To determine the fold difference between the minimum therapeutic dose and the estimated daily intake, we divide the estimated daily intake by the minimum therapeutic dose. The minimum therapeutic dose is 5 mg/day, which is equivalent to 5000 μg/day. Therefore, the fold difference is 5000 μg/day / 2.54 μg/day = 1968.5.
Interpreting this result means that the estimated daily intake of statins from drinking water is significantly lower than the minimum therapeutic dose. It indicates that even though statins might be present in drinking water, the concentration is too low to have a therapeutic effect.