Final answer:
The Seine River originates in central France, passes through Paris, and empties into the English Channel.
Step-by-step explanation:
The river that has its source in central France, flows northwest through Paris, and empties into the English Channel is the Seine River. The Seine is an important commercial waterway within the Paris Basin in the north of France. Not to be confused with the Rhine River, which flows through Germany and empties into the North Sea, or the Danube River, which flows east through major European cities before reaching the Black Sea. Historical landmarks, like the Notre Dame Cathedral, are situated on the Seine, emphasizing the river's central role in French nationhood.