Question

Which of the following is an autosomal dominant disorder?

1) cystic fibrosis
2) Achondroplasia (dwarfism)
3) Hemochromatosis (Iron storage disorder)
4) PKU (inborn error of metabolism- missing enzyme for breakdown of protein)
5) all of the above

Answer 1

An autosomal dominant disorder is a genetic disorder caused by a dominant allele on one of the non-sex chromosomes. Examples include achondroplasia (dwarfism) and hemochromatosis (iron storage disorder). PKU is an autosomal recessive disorder.

Step-by-step explanation:

An autosomal dominant disorder is a genetic disorder that is caused by a dominant allele of a single gene on an autosome, one of the 22 pairs of non-sex chromosomes. An example of an autosomal dominant disorder is achondroplasia, also known as dwarfism. In achondroplasia, a mutation in the FGFR3 gene causes abnormal bone growth, resulting in short stature. Another example is hemochromatosis, an iron storage disorder caused by a mutation in the HFE gene, leading to excessive absorption of iron from the diet. PKU, on the other hand, is an autosomal recessive disorder.