Question

Who first demonstrated transformation using mice and two strains of Streptococcus pneumoniae?

1) Griffith
2) Hershey and Chase
3) Avery, McCarty, and MacLeod
4) Watson and Crick
5) Jacob and Monod

Answer 1

Frederick Griffith was the first to demonstrate bacterial transformation using mice and two strains of Streptococcus pneumoniae. He showed that the live, nonpathogenic R strain of bacteria could be transformed into the pathogenic S strain through exposure to heat-killed S strain. This experiment proved the role of DNA in hereditary information transfer.

Step-by-step explanation:

Frederick Griffith was the first to demonstrate the process of bacterial transformation using mice and two strains of Streptococcus pneumoniae. In 1928, he showed that the live, nonpathogenic R strain of bacteria could be transformed into the pathogenic S strain through exposure to heat-killed S strain. This experiment proved that hereditary information could be transferred horizontally from one cell to another through DNA.