Question

What is the goal of the processes of positive and negative selection in the thymus?

A. Removal of allergens
B. Generation of antibodies
C. Induction of central tolerance
D. Activation of B cells
E. Removal of self-antigen-specific T cells

Answer 1

The goal of positive and negative selection in the thymus is the removal of self-antigen-specific T cells, helping to prevent autoimmune responses and ensure functional T cells are released into the bloodstream.

Step-by-step explanation:

The goal of the processes of positive and negative selection in the thymus is the removal of self-antigen-specific T cells. Positive selection ensures that T cells recognize and bind to MHC molecules, while negative selection eliminates T cells that recognize self-antigens. These processes help to prevent autoimmune responses and ensure that only functional T cells are released into the bloodstream.