Final answer:
Chromosomal regions in close proximity to the nuclear lamina are known as lamina-associated domains, which are typically heterochromatic regions with inactive genes.
Step-by-step explanation:
Chromosomal regions that are in close contact with the nuclear lamina are called lamina-associated domains. The nuclear lamina is a meshwork of intermediate filaments, primarily composed of proteins called lamins, located just inside the nuclear envelope.
It provides essential structural support to the nucleus, a feature crucial for maintaining the overall integrity and function of the cell's genetic material. During interphase, the eukaryotic chromosomes display two distinct regions identifiable by staining: heterochromatin and euchromatin. Heterochromatin, which often contacts the nuclear lamina, contains genes that are generally not expressed, whereas euchromatin has active genes that are being transcribed.