Final answer:
The question pertains to the Chicago mob boss James 'Big Jim' Colosimo, but the provided references do not include information about who he left in charge of his operations.
Step-by-step explanation:
The question 'Who did Colosimo leave in charge of his operations?' refers to a historical figure in organized crime, namely James 'Big Jim' Colosimo. Colosimo was a prominent mob boss in Chicago during the early 20th century. However, the provided reference information does not directly relate to Colosimo or the operations of his criminal empire. As such, I am unable to confidently provide an answer based on the given context.