Question

Which cytokine plays a major role in the induction of allergic responses?

A. IL-3
B. IL-2
C. IL-1
D. IL-4

Answer 1

IL-4 plays a major role in the induction of allergic responses.

Step-by-step explanation:

The cytokine that plays a major role in the induction of allergic responses is IL-4. IL-4 is released by T helper cells (TH2 cells) and stimulates B cells to produce IgE antibodies. These IgE antibodies bind to mast cells, which are then primed for a subsequent exposure to the allergen. When the allergen is encountered again, mast cells release cytokines and histamines, causing inflammation and allergic symptoms.