asked 128k views
1 vote
Describe the purpose of 2' hydroxyl group in RNA.

a. Enhances stability and functionality.
b. Initiates transcription.
c. Facilitates translation.
d. Prevents degradation.

asked
User Maxim G
by
8.2k points

1 Answer

4 votes

Final answer:

The 2' hydroxyl group in RNA contributes to the molecule's structural flexibility and diverse functionality, but does not directly protect RNA from degradation or initiate transcription or translation. Protective roles are more directly associated with 5' capping and poly-A tail addition.

Step-by-step explanation:

The purpose of the 2' hydroxyl group in RNA is often misunderstood. Unlike the 5' capping and the 3' poly-A tail, the 2' hydroxyl group does not directly protect RNA from degradation, stabilize the molecule for translation, or function in the initiation of transcription. Instead, the presence of the 2' hydroxyl in RNA allows for a higher level of structural flexibility and the potential for diverse functionality that DNA lacks due to the absence of this group. In RNA processing, however, other aspects like 5' capping with 7-methylguanosine, splicing, and polyadenylation with a poly-A tail are crucial for mRNA stability, export to the cytoplasm, and translation initiation.

answered
User Korie
by
8.2k points
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