Final answer:
After the narrator's second sighting of the ghost ship in Marquez's story, he faces the misfortune of his mother's death.
Step-by-step explanation:
In Gabriel Garcia Marquez's story "The Last Voyage of the Ghost Ship," after the narrator's second sighting of the ghost ship, he experiences the unfortunate event where his mother dies. This is a pivotal moment in the narrative, leading to a series of dark and tragic events that deeply affect the protagonist's life.