Question

Primary ossification centers begin to form in limb bones during week 8 of development.

A. True
B. False

Answer 1

B. False

The primary ossification centers in limb bones begin to form at week 12 of development, not week 8 as stated in the question, making the statement false. Ossification continues after birth with secondary centers and involves the transformation of cartilage models into bone.

Step-by-step explanation:

The statement that primary ossification centers begin to form in limb bones during week 8 of development is false. During the embryonic development of limb bones, particularly the appendicular skeleton, the main framework arises from embryonic mesenchyme. The process of endochondral ossification takes place to develop these bones.

By the twelfth week, a primary ossification center will have appeared in the diaphysis (shaft) region of the long bones, not at week 8. This center initiates the ossification process, transforming the cartilage models of the bones into actual bone tissue. The secondary ossification centers appear later, usually after birth, at each epiphysis (end) of these bones.