Final answer:
Urea levels can increase in the blood, leading to a condition called azotemia and ultimately uremia. Certain medications may need to be adjusted for patients with increased urea levels. Midazolam would require a decreased dosage in this case.
Step-by-step explanation:
Urea levels can increase in the blood, leading to a condition called azotemia and ultimately uremia. One consequence of elevated urea levels is an increased risk of developing hypertension and congestive heart failure. To manage this condition, certain medications may need to be adjusted.
In the case of a patient with increased urea levels, the medication that would require a decreased dosage is Midazolam. Midazolam is a sedative medication that is mainly metabolized by the liver, and since uremia can affect liver function, it is important to reduce the dosage to avoid potential complications.