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Which of the following acute phase reactants provides a more accurate measure of the inflammatory response?

A. Fibrinogen
B. Haptoglobin
C. C-Reactive Protein
D. Alpha 1 anti-trypsin

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Final answer:

C-Reactive Protein is a more accurate measure of inflammation and is associated with the lectin complement pathway. Type II hypersensitivity involves antibodies, while type III involves immune complex accumulation.

Step-by-step explanation:

Among the acute phase reactants, C-Reactive Protein (CRP) is considered a more accurate measure of the inflammatory response. CRP levels can rise dramatically in a short period of inflammation, making it a sensitive marker for acute inflammation. It is involved in the complement system as part of the body's immune response to help clear pathogens.

The complement activation pathway that is triggered by the binding of an acute-phase protein to a pathogen is the lectin pathway. This is one of the three main complement pathways, which also include the classical and alternate pathways.

Main mediators of type II hypersensitivity reactions include antibodies. These reactions are characterized by the immune system's response to foreign antigens on cell surfaces, leading to cell destruction. This reaction can be to a mismatched blood transfusion or autoimmunity, for example. In contrast, a type III hypersensitivity reaction, such as systemic lupus erythematosus (SLE), is induced by the accumulation of immune complexes in tissues and small blood vessels, leading to an inflammatory response.

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