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Patient receiving heparin injections that have developed red/purple/black lesions around the injection sites:

a) Heparin-induced thrombocytopenia (HIT)
b) Heparin-induced skin necrosis
c) Heparin-induced vasculitis
d) Heparin-induced angioedema

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User Mrosiak
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1 Answer

3 votes

Final Answer:

The patient's symptoms, specifically the development of red/purple/black lesions around the injection sites, are indicative of Heparin-induced skin necrosis. Thus the correct option is (b).

Step-by-step explanation:

Heparin-induced skin necrosis is a rare but severe complication associated with the use of heparin. This condition typically presents as painful, erythematous, and necrotic lesions at the injection sites. The pathophysiology involves the formation of immune complexes, which activate the clotting cascade, leading to thrombosis and subsequent skin necrosis. Heparin-induced skin necrosis is more commonly observed in patients with heparin-induced thrombocytopenia (HIT), where there is an immune-mediated decrease in platelet count. The development of necrotic lesions is attributed to the procoagulant effect of heparin and the associated thrombotic events, resulting in compromised blood supply to the affected tissues.Thus the correct option is (b).

In the context of the given options:

Heparin-induced thrombocytopenia (HIT) primarily involves a decrease in platelet count and is associated with thrombosis, but it does not directly cause skin necrosis.

Heparin-induced vasculitis typically manifests as purpura and involves inflammation of blood vessel walls, not necrosis around injection sites.

Heparin-induced angioedema is characterized by swelling of deeper layers of the skin, which is different from the necrotic lesions described.

Therefore, the presence of red/purple/black lesions around the injection sites aligns most closely with the diagnosis of heparin-induced skin necrosis, emphasizing the importance of prompt recognition and appropriate management to mitigate further complications.

answered
User Harsha Basnayake
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