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Which cell junction encircles a cell like a belt at its apical end and binds a cell to its surrounding neighbors? May also transmit signals between those neighboring cells as well.

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Final Answer:

The cell junction that encircles a cell like a belt at its apical end, binding a cell to its surrounding neighbors and potentially transmitting signals between those neighboring cells, is called a _tight junction_.

Step-by-step explanation:

Tight junctions are integral components of cell junctions in epithelial tissues, providing a seal between adjacent cells. The name "tight junction" reflects the tightness of the seal created by these junctions, preventing the leakage of substances between cells.

Structurally, tight junctions involve the fusion of outer cell membrane layers, forming a continuous belt-like structure around the apical end of cells. This physical connection not only serves as a barrier but also facilitates communication between neighboring cells.

The main function of tight junctions is to maintain the integrity of epithelial cell layers by preventing the passage of ions, water, and other molecules through the intercellular space. This is crucial for the selective transport of substances across epithelial barriers, such as those in the digestive tract and kidneys.

Tight junctions also play a role in cell signaling, allowing the transmission of signals between adjacent cells. The proteins forming tight junctions, including claudins and occludins, contribute to the structural integrity and selective permeability of these junctions.

Understanding the role of tight junctions is essential in various physiological and pathological contexts. Disruptions in tight junction function can lead to increased permeability, compromising the integrity of epithelial barriers and contributing to conditions such as inflammatory bowel disease. Therefore, tight junctions are pivotal in maintaining tissue homeostasis and regulating cellular interactions in multicellular organisms.

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User Stephen Rauch
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