Question

The extent of the haplotype block surrounding a disease mutation depends on which two of the following factors?

A Marker phasing
B Marker association
C Recombination frequency in the region
D Number of generations since the disease mutation arose
E Marker repulsion

Answer 1

The extent of the haplotype block surrounding a disease mutation depends on marker phasing and recombination frequency in the region.

Step-by-step explanation:

The extent of the haplotype block surrounding a disease mutation depends on two factors: Marker phasing and Recombination frequency in the region. Marker phasing refers to the arrangement of genetic markers on a chromosome, which can affect the size of the haplotype block. Recombination frequency in the region determines the likelihood of genetic recombination occurring and breaking apart the haplotype block.