Final answer:
Changing the TLC solvent to 80:20 hexane:ethyl acetate would have an effect on the R values. The R value is a measure of how far a compound travels on the TLC plate relative to the solvent front. In general, a more polar solvent will result in a lower R value, while a less polar solvent will result in a higher R value for a given compound.
Step-by-step explanation:
Changing the TLC solvent to 80:20 hexane:ethyl acetate would have an effect on the Rt values.
The Rt value, or retention factor, is a measure of how far a compound travels on the TLC plate relative to the solvent front. It is used to identify and compare compounds.
In general, a more polar solvent will result in a lower Rt value, while a less polar solvent will result in a higher Rt value for a given compound. In this case, changing the TLC solvent to 80:20 hexane:ethyl acetate would make the solvent less polar compared to the original solvent, which was 10% MeOH in CH2Cl2.