Final answer:
The Stratum spinosum is the layer rich in RNA and has notable intercellular bridges known as desmosomes. It is located above the stratum basale and comprises several layers of keratinocytes and Langerhans cells.
Step-by-step explanation:
The layer of the epidermis that contains cells rich in ribonucleic acid (RNA) and has prominent intercellular bridges or desmosomes is Stratum spinosum. This layer is characterized by its spiny appearance due to the presence of desmosomes, which are specialized structures that hold cells together and provide structural support. The stratum spinosum is above the stratum basale and is known for being the thickest of the epidermal layers.
It consists of eight to ten layers of keratinocytes. These cells begin to accumulate keratin and become more durable as they are pushed upward. Moreover, the stratum spinosum houses immunologically active Langerhans cells, which function as a macrophage by engulfing bacteria, foreign particles, and damaged cells found in this layer.