Question

Which of the following is most ofter undergoing successful rearrangement to prevent the formation of auto reactive lymphocyte receptors?

A. Ig Light kappa chain
B. TCR alpha chain
C. Ig Heavy mu chain
D. Both A and B
E. all of the above

Answer 1

The correct answer is option D, Both A and B. Both the Ig Light kappa chain and TCR alpha chain can undergo successful rearrangement to prevent the formation of auto reactive lymphocyte receptors.

Step-by-step explanation:

The correct answer is option D, Both A and B. Both the Ig Light kappa chain (A) and TCR alpha chain (B) can undergo successful rearrangement to prevent the formation of auto reactive lymphocyte receptors.

B cells, like T cells, use genetic rearrangement of gene segments to provide the necessary diversity of receptor specificities. The variable region of the BCR heavy chain is made up of V, D, and J segments, similar to the ß chain of the TCR. The variable region of the BCR light chain is made up of V and J segments, similar to the a chain of the TCR.

Therefore, both the Ig Light kappa chain and TCR alpha chain undergo successful rearrangement to prevent auto reactive lymphocyte receptors.