Question

Which of the following would you use to inhibit the contraction of muscle in vitro as a control for an experiment you are conducting?

A) a drug that increases sarcoplasm Ca₂₊ concentration
B) a motor protein ATPase inhibitor
C) a Ca₂₊-ATPase inhibitor
D) a drug that increases T-tubule depolarization
E) All would inhibit muscle contraction.

Answer 1

To inhibit muscle contraction in vitro, you would use a Ca²⁺-ATPase inhibitor to prevent the release of calcium ions from the sarcoplasmic reticulum.

Step-by-step explanation:

To inhibit the contraction of muscle in vitro as a control for an experiment, you would use a Ca²⁺-ATPase inhibitor. This inhibitor would prevent the release of calcium ions (Ca²⁺) from the sarcoplasmic reticulum, thereby blocking the contraction process. A Ca²⁺-ATPase inhibitor would specifically interfere with the step where calcium ions are released and initiate filament sliding in the muscle fiber.