Final answer:
The transfusion least likely to cause a reaction is ABO-compatible, Rh-compatible because matching both the ABO and Rh factors is crucial in preventing immediate and delayed hemolytic transfusion reactions. The correct option is C) ABO-compatible, Rh-compatible
Step-by-step explanation:
The transfusion that would be least likely to cause a transfusion reaction is C) ABO-compatible, Rh-compatible. This is because both the ABO blood group and the Rh factor must match between donor and recipient to prevent adverse reactions. ABO compatibility ensures that the recipient's body does not produce antibodies that would attack the donated blood cells.
The Rh factor, mainly the D antigen, is also crucial as Rh-positive individuals can receive both Rh-positive and Rh-negative blood without issues, whereas Rh-negative individuals should only receive Rh-negative blood to prevent the production of anti-Rh antibodies and a possible delayed hemolytic transfusion reaction.
It is essential that both the ABO blood group system and the Rh factor are taken into consideration during transfusions to avoid both immediate and delayed transfusion reactions, which can range from mild to life-threatening. The correct option is C) ABO-compatible, Rh-compatible