asked 52.7k views
5 votes
Which of the following describes the histones associated with the nucleosomes of inactive genes?

A. Acetylated
B. Methylated
C. Hypoacetylated
D. Hyperacetylated

asked
User Fluminis
by
7.6k points

1 Answer

4 votes

Final answer:

Inactive genes are associated with hypermethylated DNA regions and deacetylated histones. Histone acetylation and methylation play important roles in regulating gene expression. Hence, B) is correct.

Step-by-step explanation:

Inactive genes are associated with hypermethylated DNA regions and deacetylated histones. These modifications cause the nucleosomes to pack tightly together, resulting in transcriptional repression and inactivation of the genes. Histone acetylation and methylation play important roles in regulating gene expression.

Histone acetylation tends to unwind nucleosomes and open the DNA for transcription, while histone methylation can either open or suppress transcription depending on the specific lysines or arginines modified. Therefore, the correct answer is B. Methylated.

answered
User Konzo
by
8.9k points
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