Final answer:
CSER structures, or the cellular stress fiber network, can develop nematic order in response to changes in substrate rigidity. This nematic order is maximal in an optimal range of substrate rigidity and is small for very small or very large rigidities.
Step-by-step explanation:
CSER structures, or the cellular stress fiber network, are related to each other through the development of nematic order in response to changes in substrate rigidity. Research suggests that cells with anisotropic shapes on substrates of intermediate rigidity will spontaneously exhibit CSER nematic order. The nematic order of the CSER is maximal in an optimal range of substrate rigidity and is small for very small or very large rigidities.