Final answer:
The number that will appear in column C in row 22 is 39.
Step-by-step explanation:
To determine the number that will appear in column C in row 22, we can observe the pattern and determine the rule that governs it. Since the integers are arranged in three columns, we can see that the integers in column C form a sequence starting from 18. The pattern is that the first number in column C is 18, and each subsequent number is obtained by adding 1 to the previous number. Therefore, for row 22, the number in column C will be 18 + (22-1) = 39.