Question

arrange the steps to outline phosphorylation of a serine residue by a protein kinase.Answer Bank:ADP is released from the active site of the kinaseThe γ-phosphate from ATP is transferred to the hydroxyl group of a serine residue within the substrateATP binds to the active site of the kinaseThe substrate binds to the active site of the kinaseThe phosphorylated substrate is released from the active site of the kinase

Answer 1

Phosphorylation of a serine residue by a protein kinase involves several steps: ATP binding, substrate binding, transfer of phosphate, release of ADP, and release of the phosphorylated substrate.

Step-by-step explanation:

In the process of phosphorylation, a phosphate group (PO4³) is added to the hydroxyl group of a serine residue by a protein kinase. Here are the steps to outline phosphorylation:

1. ATP binds to the active site of the kinase.
2. The substrate binds to the active site of the kinase.
3. The γ-phosphate from ATP is transferred to the hydroxyl group of a serine residue within the substrate.
4. ADP is released from the active site of the kinase.
5. The phosphorylated substrate is released from the active site of the kinase.