Question

Please identify the type of protein complex that will be recruited to the enhancer sequence of a gene by pioneer transcription activator.

A. HAT complex
B. HDAC complex
C. Transcription repressor complex
D. HAT complex and HDAC complex
E. HDAC complex and transcription repressor complex

Answer 1

A. HAT complex

The type of protein complex that will be recruited to the enhancer sequence of a gene by a pioneer transcription activator is a HAT (Histone Acetyl Transferase) complex. HAT complexes are responsible for acetylating histones which are necessary for enhancing transcription and making chromatin more accessible.